Article
Clinical associations of the risk alleles of HLA-Cw6 and CCHCR1*WWCC in psoriasis.
Acta dermato-venereologica - 1 Jan 2007
Suomela Sari, Kainu Kati, Onkamo Päivi, Tiala Inkeri, Himberg Johan, Koskinen Lotta, Snellman Erna, Karvonen Seija-Liisa, Karvonen Jaakko, Uurasmaa Tutta, Reunala Timo, Kivikäs Kristiina, Jansén Christer T, Holopainen Päivi, Elomaa Outi, Kere Juha, Saarialho-Kere Ulpu
Abstract excerpt
The PSORS1 locus is the consistently replicated genetic risk factor for psoriasis. Clinical associations with the main marker allele of PSORS1, HLA-Cw6, have been addressed in a number of studies, but clinical associations have not been used as a way to distinguish the effects of the neighbouring candidate genes in PSORS1. Our results show that HLA-Cw6 and CCHCR1 risk allele associations with clinical features of...
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