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Article

Polymorphism in HTR3D shows different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy.

Pharmacogenomics - 1 Jul 2010

Hammer Christian, Fasching Peter A, Loehberg Christian R, Rauh Claudia, Ekici Arif B, Jud Sebastian M, Bani Mayada R, Beckmann Matthias W, Strick Reiner, Niesler Beate

Abstract excerpt

AIMS: Serotonin (5-hydroxytryptamine 3; 5-HT(3)) receptors are involved in chemotherapy-induced nausea and vomiting (CINV), and 5-HT(3) antagonists are part of the 'gold standard' antiemetic treatment during chemotherapy. We investigated the correlation of common variants in 5-HT(3) receptor subunit genes with the occurrence of CINV. MATERIALS & METHODS: A total of 110 previously characterized chemotherapy-naive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20602613
DOI: 10.2217/pgs.10.67

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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