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Article

A review of the literature on the relationships between genetic polymorphisms and chemotherapy-induced nausea and vomiting.

Critical reviews in oncology/hematology - 1 Jan 2018

Singh Komal P, Dhruva Anand A, Flowers Elena, Kober Kord M, Miaskowski Christine

Abstract excerpt

Despite current advances in antiemetic treatments, between 30% to and 60% of oncology patients experience chemotherapy-induced nausea (CIN) and 13% to 33% report chemotherapy-induced vomiting (CIV). Inter-individual differences are observed in the occurrence and severity of chemotherapy-induced nausea and vomiting (CINV). This review summarizes and critiques studies on associations between occurrence and severity...

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Share to Antineoplastic Agents
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Nausea

Share to Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Receptors, Serotonin, 5-HT3

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Source

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Identifiers

PMID: 29279099
DOI: 10.1016/j.critrevonc.2017.11.012
PMCID: PMC5777158

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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