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Article

Association between variants of 5-hydroxytryptamine receptor 3C (HTR3C) and chemotherapy-induced symptoms in women receiving adjuvant treatment for breast cancer.

Breast cancer research and treatment - 1 Feb 2014

Pud Dorit, Har-Zahav Gil, Laitman Yael, Rubinek Tami, Yeheskel Adva, Ben-Ami Sarah, Kaufman Bella, Friedman Eitan, Symon Zvi, Wolf Ido

Abstract excerpt

Administration of chemotherapy is associated with a wide array of symptoms affecting quality of life. Genetic risk factors for severity of chemotherapy-induced symptoms have not been determined. The present study aimed to explore the associations between polymorphisms in candidate genes and chemotherapy-induced symptoms. Women treated with at least two cycles of adjuvant doxorubicin and cyclophosphamide, with or...

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Share to Antineoplastic Combined Chemotherapy Protocols
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Serotonin, 5-HT3

Source

Identifiers

PMID: 24477975
DOI: 10.1007/s10549-014-2832-y

Genes

COMT
GCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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