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Article

Aberrant repair of etheno-DNA adducts in leukocytes and colon tissue of colon cancer patients.

Free radical biology & medicine - 15 Sept 2010

Obtułowicz Tomasz, Winczura Alicja, Speina Elzbieta, Swoboda Maja, Janik Justyna, Janowska Beata, Cieśla Jarosław M, Kowalczyk Paweł, Jawien Arkadiusz, Gackowski Daniel, Banaszkiewicz Zbigniew, Krasnodebski Ireneusz, Chaber Andrzej, Olinski Ryszard, Nair Jagadesaan, Bartsch Helmut, Douki Thierry, Cadet Jean, Tudek Barbara

Abstract excerpt

To assess the role of lipid peroxidation-induced DNA damage and repair in colon carcinogenesis, the excision rates and levels of 1,N(6)-etheno-2'-deoxyadenosine (epsilondA), 3,N(4)-etheno-2'-deoxycytidine (epsilondC), and 1,N(2)-etheno-2'-deoxyguanosine (1,N(2)-epsilondG) were analyzed in polymorphic blood leukocytes (PBL) and resected colon tissues of 54 colorectal carcinoma (CRC) patients and PBL of 56 healthy...

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Identifiers

PMID: 20600828
DOI: 10.1016/j.freeradbiomed.2010.06.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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