Article
Escape of intracellular Shigella from autophagy requires binding to cholesterol through the type III effector, IcsB.
Microbes and infection - 1 Nov 2010
Kayath Christian Aimé, Hussey Seamus, El hajjami Nargisse, Nagra Karan, Philpott Dana, Allaoui Abdelmounaaïm
Abstract excerpt
Type III secretion systems are present in many pathogenic bacteria and mediate the translocation of bacterial effectors into host cells. Identification of host targets of these effectors is crucial for understanding bacterial virulence. IcsB, a type III secretion effector, helps Shigella to evade...
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