Article

The <i>Shigella</i> type III effector protein OspB is a cysteine protease

2021-09-01

Abstract excerpt

The type III secretion system is required for virulence of many pathogenic bacteria. Bacterial effector proteins delivered into target host cells by this system modulate host signaling pathways and processes in a manner that promotes infection. Here, we define the activity of the effector protein OspB of the human pathogen Shigella spp., the etiological agent of shigellosis and dysenteric disease. Using the yeast...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7b590f66-178a-55ba-8549-e6b3b2704528
DOI: 10.1101/2021.09.01.458261

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The <i>Shigella</i> type III effector protein OspB is a cysteine proteaseDOI 10.1101/2021.09.01.458261Read

Shigella IpaH Family Effectors as a Versatile Model for Studying Pathogenic BacteriaSemantic proximity Read

Yeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulation.Semantic proximity Read

Identification of a Novel Salmonella Type III Effector by Quantitative Secretome Profiling.Semantic proximity Read

Molecular Pathogenesis of<i>Shigella</i>spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III SecretionSemantic proximity Read

A new paradigm of bacteria-gut interplay brought through the study of <bold>Shigella</bold>Semantic proximity Read

Endopeptidase regulation as a novel function of the Zur-dependent zinc starvation responseSemantic proximity Read

Identification of a family of <i>Vibrio</i> type III secretion system effectors that contain a conserved serine/threonine kinase domainSemantic proximity Read

Formylglycine-generating enzyme-like proteins constitute a novel family of widespread type VI secretion system immunity proteinsSemantic proximity Read

Identification of A Putative T6SS Immunity Islet in Salmonella TyphiSemantic proximity Read

A holin and an endopeptidase are essential for chitinolytic protein secretion in Serratia marcescensSemantic proximity Read

Escape of intracellular Shigella from autophagy requires binding to cholesterol through the type III effector, IcsB.Semantic proximity Read

Topology and contribution to the pore channel lining of plasma membrane-embedded <i>S. flexneri</i> type 3 secretion translocase IpaBSemantic proximity Read