Article
Genetic polymorphism of methylenetetrahydrofolate reductase G1793A, hyperhomocysteinemia, and folate deficiency correlate with ulcerative colitis in central China.
Journal of gastroenterology and hepatology - 1 Jun 2010
Jiang Yi, Zhao Jie, Jiang Ting, Ge Liuqing, Zhou Feng, Chen Zhitao, Lei Yuan, Huang Sha, Xia Bing
Abstract excerpt
BACKGROUND AND AIMS: Methylenetetrahydrofolate reductase (MTHFR) encoding genes were associated with ulcerative colitis in Chinese in our previous study. We further studied association of a new polymorphism of MTHFR G1793A with ulcerative colitis and assessed relationship of this polymorphism with hyperhomocysteinemia (HHcy, > or = 15 mmol/L) and deficiency of folate (< or = 7 nmol/L) and vitamin B(12) (< or =...
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