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Article

Association of ulcerative colitis with transcobalamin II gene polymorphisms and serum homocysteine, vitamin B12, and folate levels in Chinese patients.

Immunogenetics - 1 Jul 2017

Zheng Shuzi, Yang Wei, Wu Chaoqun, Sun Liang, Lin Daopo, Lin Xiuqing, Jiang Lijia, Ding Ran, Jiang Yi

Abstract excerpt

It has been reported that abnormal elevation of homocysteine is quite prevalent in ulcerative colitis (UC) patients. We attempted to explore the relationship of UC with transcobalamin II (TCN2) gene polymorphisms and serum homocysteine, vitamin B12, and folate levels in Chinese patients. TCN2 (rs1801198, rs9606756) genotypes were detected by the improved multiple ligase detection reaction (iMLDR) technique in 527...

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Identifiers

PMID: 28526947
DOI: 10.1007/s00251-017-0998-2

Genes

TCN2

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