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Article

Predictive values of amino acid sequences of the core and NS5A regions in antiviral therapy for hepatitis C: a Japanese multi-center study.

Journal of gastroenterology - 1 Jan 2009

Okanoue Takeshi, Itoh Yoshito, Hashimoto Hiroaki, Yasui Kohichiroh, Minami Masahito, Takehara Tetsuo, Tanaka Eiji, Onji Morikazu, Toyota Joji, Chayama Kazuaki, Yoshioka Kentaro, Izumi Namiki, Akuta Norio, Kumada Hiromitsu

Abstract excerpt

BACKGROUND: Chronic hepatitis C (CHC) genotype 1b patients with high viral load are resistant to peginterferon (PEG-IFN) and ribavirin (RBV) combination therapy, especially older and female patients. METHODS: To elucidate the factors affecting early and sustained viral responses (EVR and SVR), 409 genotype 1b patients CHC with high viral loads who had received 48 weeks of PEG-IFN/RBV therapy were enrolled. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19517057
DOI: 10.1007/s00535-009-0087-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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