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Article

Revisiting Crohn's disease as a primary immunodeficiency of macrophages.

The Journal of experimental medicine - 31 Aug 2009

Casanova Jean-Laurent, Abel Laurent

Abstract excerpt

Despite two decades of mouse immunology and human genetics studies, the pathogenesis of Crohn's disease (CD) remains elusive. New clinical investigations suggest that CD may be caused by inborn errors of macrophages. These errors may result in impaired attraction of granulocytes to the gut wall,...

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Identifiers

PMID: 19687225
DOI: 10.1084/jem.20091683
PMCID: PMC2737171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19687225-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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