Article
Role of CNR1 polymorphisms in moderating the effects of psychosocial adversity on impulsivity in adolescents.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2015
Buchmann Arlette F, Hohm Erika, Witt Stephanie H, Blomeyer Dorothea, Jennen-Steinmetz Christine, Schmidt Martin H, Esser Günter, Banaschewski Tobias, Brandeis Daniel, Laucht Manfred
Abstract excerpt
Enhanced endocannabinoid signaling has been implicated in typically adolescent behavioral features such as increased risk-taking, impulsivity and novelty seeking. Research investigating the impact of genetic variants in the cannabinoid receptor 1 gene (CNR1) and of early rearing conditions has demonstrated that both factors contribute to the prediction of impulsivity-related phenotypes. The present study aimed to...
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