Article
[Detection of HBV resistant mutations related to lamivudine, adefovir and entecavir by reverse hybridization technique].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Jun 2010
Liu Yan-Chen, Zhang Wen-Lu, Hu Yuan, Zhao Li, Lai Guo-Qi, Hu Jie-Li, Yang Feng, Huang Ai-Long
Abstract excerpt
OBJECTIVES: To establish a method for simultaneous detection of HBV resistant mutations associated with three kinds of nucleoside analogues. METHODS: According to 981 HBV complete sequences in GenBank, two pairs of conserved primers labeled with digoxigenin were synthesized to amplify the region...
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