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Article

[Detection of HBV resistant mutations related to lamivudine, adefovir and entecavir by reverse hybridization technique].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Jun 2010

Liu Yan-Chen, Zhang Wen-Lu, Hu Yuan, Zhao Li, Lai Guo-Qi, Hu Jie-Li, Yang Feng, Huang Ai-Long

Abstract excerpt

OBJECTIVES: To establish a method for simultaneous detection of HBV resistant mutations associated with three kinds of nucleoside analogues. METHODS: According to 981 HBV complete sequences in GenBank, two pairs of conserved primers labeled with digoxigenin were synthesized to amplify the region of HBV reverse transcriptase. To detect non-synonymous amino acid substitutions associated with lamivudine, adefovir...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20587309
DOI: 10.3760/cma.j.issn.1007-3418.2010.06.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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