Article
[Age-related and clinical-pathogenetic features of colorectal cancer associated with status of K-ras gene].
Advances in gerontology = Uspekhi gerontologii - 1 Jan 2012
Beliaeva A V, Ianus G A, Suspithyn E N, Zaĭtseva O A, Iatsuk O S, Moiseenko A B, Guliaev A V, Imianitov E N
Abstract excerpt
Activating mutation in K-ras gene is a key event in the pathogenesis of colon carcinoma. This study analyses frequency of this mutation in different age groups of colorectal cancer patients residing in North-Western Russia, and examines its relationship with essential clinical characteristics of tumor disease.
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