Article
The role of MSP I CYP1A1 gene polymorphism in the development of uterine fibroids.
Fertility and sterility - 1 Dec 2010
Barão Marco Antônio, Oliveira Emerson, Gomes Mariano Tamura Vieira, da Silva Ismael Dale Cotrim Guerreiro, Sartori Marair Gracio Ferreira, Girão Manoel João Batista Castello, Castro Rodrigo de Aquino
Abstract excerpt
The cytochrome P-450 1A1 (CYPA1A) gene plays an important role in the metabolization of estrogen and is therefore a candidate marker for fibroids. In a case-control study, we were unable to demonstrate any association between MSP I CYP1A1 polymorphism and the risk of leiomyoma in Brazilian women.
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