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Article

Association of the CYP17 gene polymorphism with risk for uterine leiomyoma in Brazilian women.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jul 2008

Vieira Lucinda Coelho Esperança, Gomes Mariano Tamura Vieira, Castro Rodrigo de Aquino, de Souza Naiara Correia Nogueira, da Silva Ismael Dale Cotrim Guerreiro, Baracat Edmund Chada, Girão Manoel Joao Batista Castello

Abstract excerpt

BACKGROUND: Uterine leiomyoma is the most common pelvic tumor in women of reproductive age. It is well established that endogenous sex hormones are involved in disease pathogenesis, and polymorphisms in genes encoding enzymes which act in the metabolism of steroid hormones, such as that for cytochrome P450c17alpha enzyme (CYP17), may therefore play a role in fibroid genesis. Variations in this gene have been...

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PMID: 18645709
DOI: 10.1080/09513590802131830

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Association of the CYP17 gene polymorphism with risk for uterine leiomyoma in Brazilian women.PMID 18645709Read ↗

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