Article
Development and evaluation of an automated hepatitis C virus NS5B sequence-based subtyping assay.
Clinical chemistry and laboratory medicine - 1 Aug 2010
Koletzki Diana, Dumont Stéphanie, Vermeiren Hans, Fevery Bart, De Smet Pieter, Stuyver Lieven J
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) genotyping and accurate subtype determination is becoming increasingly important to better understand viral evolution, the development of resistance to STAT-C, and possibly even for the treatment and management of chronic HCV-infected patients. METHODS: A subtyping assay based on a 329-bp sequence of the NS5B region, together with an automated subtype interpretation tool was...
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