Article
Functional glutathione peroxidase 3 polymorphisms associated with increased risk of Taiwanese patients with gastric cancer.
Clinica chimica acta; international journal of clinical chemistry - 9 Oct 2010
Wang Jaw-Yuan, Yang I-Ping, Wu Deng-Chyang, Huang Szu-Wei, Wu Jeng-Yih, Juo Suh-Hang Hank
Abstract excerpt
BACKGROUND: Glutathione peroxidase 3 (GPX3) can enhance an antioxidant's capacity and reduce genomic damage caused by oxidants and thus influence tumorigenesis. We investigated the role of GPX3 as a risk of gastric cancer. METHODS: We first conducted a case-control study to test for the association between 5 tagging single nucleotide polymorphisms (SNPs) of GPX3 and the risk of gastric cancer in Chinese....
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