Association of H pylori cagA and vacA genotypes and IL-8 gene polymorphisms with clinical outcome of infection in Iranian patients with gastrointestinal diseases.

doi:10.3748/wjg.v12.i32.5205

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Article

Association of H pylori cagA and vacA genotypes and IL-8 gene polymorphisms with clinical outcome of infection in Iranian patients with gastrointestinal diseases.

World journal of gastroenterology - 28 Aug 2006

Kamali-Sarvestani Eskandar, Bazargani Abdulah, Masoudian Malihe, Lankarani Kamran, Taghavi Ali-Reza, Saberifiroozi Mehdi

Abstract excerpt

AIM: To find out if a functional promoter polymorphism in the IL-8 gene along with cagA status and polymorphisms in vacA gene influence the type of diseases in Iranian patients infected by H pylori. METHODS: IL-8 -251 A/T polymorphism was genotyped by oligonucleotide allele specific PCR (ASO-PCR) in a sample of 233 patients with H pylori infection undergoing upper gastrointestinal endoscopy. The presence of cagA...

Topics

Adult
Alleles
Antigens, Bacterial
Bacterial Proteins
Female
Gastrointestinal Diseases
Genotype
Helicobacter Infections
Helicobacter pylori
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-8

Iran

Male

Middle Aged

Polymerase Chain Reaction

Polymorphism, Genetic

Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 16937534
DOI: 10.3748/wjg.v12.i32.5205
PMCID: PMC4088021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16937534-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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