Article
The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle.
Genome biology - 1 Jan 2010
Ferrezuelo Francisco, Colomina Neus, Futcher Bruce, Aldea Martí
Abstract excerpt
BACKGROUND: The G1-to-S transition of the cell cycle in the yeast Saccharomyces cerevisiae involves an extensive transcriptional program driven by transcription factors SBF (Swi4-Swi6) and MBF (Mbp1-Swi6). Activation of these factors ultimately depends on the G1 cyclin Cln3. RESULTS: To determine the transcriptional targets of Cln3 and their dependence on SBF or MBF, we first have used DNA microarrays to...
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