Article
Plasmodium vivax circumsporozoite genotypes: a limited variation or new subspecies with major biological consequences?
Malaria journal - 23 Jun 2010
Souza-Neiras Wanessa C, Storti-Melo Luciane M, Cassiano Gustavo C, Couto Vanja S C A, Couto Alvaro A R A, Soares Irene S, Carvalho Luzia H, Cunha Maristela G, Póvoa Marinete M, Herrera Socrates, Herrera Myriam A, Rossit Andrea R M, Carareto Claudia M A, Machado Ricardo L D
Abstract excerpt
BACKGROUND: Plasmodium vivax circumsporozoite variants have been identified in several geographical areas. The real implication of the genetic variation in this region of the P. vivax genome has been questioned for a long time. Although previous studies have observed significant association between VK210 and the Duffy blood group, we present here that evidences of this variation are limited to the CSP central...
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