Article
[The enhancement of DNA binding ability of a mutated E2 (A338V) protein of HPV-2].
Bing du xue bao = Chinese journal of virology - 1 May 2010
Pan Ming-ming, Gao Chen, Li Xiao-li, Gong Han-shi, Shi Qi, Yuan Yu-kang, Fan Gui-xiang, Dong Xiao-ping
Abstract excerpt
HPV-2 is a very common type of HPV which causes common warts. The E2 protein of virus can repress the activity of the viral early promoter through binding to the specific binding sites in viral LCR. Previously we reported that the repression of a mutated E2 protein of HPV-2 isolated from a patient with huge common wart on the viral early promoter was obviously decreased, and A338V mutation located at the C...
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