Article
HPV-2 isolates from patients with huge verrucae vulgaris possess stronger promoter activities.
Intervirology - 1 Jan 2007
Lei Yan-Jun, Wang Chen, Gao Chen, Jiang Hui-Ying, Chen Jian-Ming, Han Jun, Yuan Yu-Kang, Dong Xiao-Ping
Abstract excerpt
OBJECTIVES: To assess the influences of the mutations within the long control region (LCR) and E2 open reading frame (ORF) of the human papillomavirus-2 (HPV-2) isolates from patients with extensive verrucae vulgaris with cutaneous horns in the activities of the viral early promoters. METHODS: A PCR method was applied for screening HPV DNA in the lesion specimens and the complete HPV-2 genomes was analyzed....
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