S‐Gal®, A novel ¹H MRI reporter for β‐galactosidase

Abstract excerpt

Reporter genes and associated enzyme activity are becoming increasingly significant for research in vivo. The lacZ gene and beta-galactosidase (beta-gal) expression have long been exploited as reporters of biologic manipulation at the molecular level, and a noninvasive detection strategy based on proton MRI is particularly attractive. 3,4-Cyclohexenoesculetin beta-D-galactopyranoside (S-Gal) is a commercial...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Advanced MRI Techniques and Applications
• Share to Cancer, Hypoxia, and Metabolism
• Share to Enzyme Structure and Function