Article
<sup>19</sup>F MRI Monitoring of Gene Expression in Living Cells through Cell‐Surface β‐Lactamase Activity
6 Jul 2012
Abstract excerpt
Magnetic resonance imaging provides important intravital information on deep tissues that cannot be visualized by other methods. Although we had previously developed an off/on switching (19)F MRI probe to monitor reporter enzyme activity on the basis of the paramagnetic relaxation enhancement effect, it was difficult to monitor biological events in living cells because the (19)F MRI probe did not permeate living...
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