Article
Metalloprotein-based MRI probes.
FEBS letters - 17 Apr 2013
Matsumoto Yuri, Jasanoff Alan
Abstract excerpt
Metalloproteins have long been recognized as key determinants of endogenous contrast in magnetic resonance imaging (MRI) of biological subjects. More recently, both natural and engineered metalloproteins have been harnessed as biotechnological tools to probe gene expression, enzyme activity, and analyte concentrations by MRI. Metalloprotein MRI probes are paramagnetic and function by analogous mechanisms to...
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