Article
Probing local structural fluctuations in myoglobin by size-dependent thiol-disulfide exchange.
Protein science : a publication of the Protein Society - 1 Aug 2010
Stratton Margaret M, Cutler Thomas A, Ha Jeung-Hoi, Loh Stewart N
Abstract excerpt
All proteins undergo local structural fluctuations (LSFs) or breathing motions. These motions are likely to be important for function but are poorly understood. LSFs were initially defined by amide hydrogen exchange (HX) experiments as opening events, which expose a small number of backbone amide...
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