Article
Exploring Compactness and Dynamics of Apomyoglobin.
Proteins - 1 May 2025
Glyakina Anna V, Suvorina Mariya Y, Dovidchenko Nikita V, Katina Natalya S, Surin Alexey K, Galzitskaya Oxana V
Abstract excerpt
Hydrogen-deuterium exchange mass spectrometry (HDX-MS) approach has become a valuable analytical complement to traditional methods. HDX-MS allows the identification of dynamic surfaces in proteins. We have shown that the introduction of various mutations into the amino acid sequence of whale apomyoglobin (apoMb) leads to a change in the number of exchangeable hydrogen atoms, which is associated with a change in...
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