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Article

EphA2 as a Novel Molecular Marker and Target in Glioblastoma Multiforme

1 Oct 2005

Abstract excerpt

We investigated the presence of EphA2, and its ligand, ephrinA1, in glioblastoma multiforme (GBM), a malignant neoplasm of glial cells, and normal brain. We also initially examined the functional importance of the interaction between EphA2 and ephrinA1 in glioma cells. Expression and localization of EphA2 and ephrinA1 in human GBM and normal brain were examined using Western blotting, immunofluorescence, and...

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PMID: 16254188
DOI: 10.1158/1541-7786.mcr-05-0056

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