Article
Biological significance of EPHA2 expression in neuroblastoma.
International journal of oncology - 1 Oct 2009
Kung Bing, Zhao Huaqing, Hicks Sakeenah L, Tang Xao X, Ikegaki Naohiko
Abstract excerpt
Neuroblastoma is a pediatric solid tumor that exhibits striking clinical bipolarity. Despite extensive efforts to treat unfavorable neuroblastoma, survival rate of children with the disease is among the lowest. Previous studies suggest that EPHA2, a member of the EPH family receptor kinases, can either promote or suppress cancer cell growth depending on cellular contexts. In this study, we investigated the...
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