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Article

Evidence that bone mineral density plays a role in degenerative disc disease: the UK Twin Spine study.

Annals of the rheumatic diseases - 1 Dec 2010

Livshits Gregory, Ermakov Sergey, Popham Maria, Macgregor Alex J, Sambrook Philip N, Spector Timothy D, Williams Frances M K

Abstract excerpt

OBJECTIVE: Osteoarthritis (OA) and osteoporosis are often considered to lie at opposite ends of a spectrum of bone phenotypes. Lumbar degenerative disc disease (LDD) may be associated with low back pain (LBP) and is similar in many ways to OA. LDD is reported in small studies to be associated with increased spine bone mineral density (BMD). The present work aimed to confirm this association in a large population...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Bone Density
Diseases in Twins
Epidemiologic Methods
Female
Genetic Predisposition to Disease
Hip Joint
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Intervertebral Disc Degeneration

Lumbar Vertebrae

Magnetic Resonance Imaging

Middle Aged

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 20570838
DOI: 10.1136/ard.2010.131441
PMCID: PMC3002767

Genes

LBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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