Article
Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice.
Proceedings of the National Academy of Sciences of the United States of America - 6 Jul 2010
Dhar Neeraj, McKinney John D
Abstract excerpt
Tuberculosis (TB) is notoriously difficult to cure, requiring administration of multiple antibiotics for 6 mo or longer. Conventional anti-TB drugs inhibit biosynthetic processes involved in cell growth and division, such as DNA replication, RNA transcription, protein translation, and cell wall b...
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