Article
Mechanisms involved in the intrinsic isoniazid resistance of Mycobacterium avium.
Molecular microbiology - 1 Mar 1998
Mdluli K, Swanson J, Fischer E, Lee R E, Barry C E
Abstract excerpt
Isoniazid (INH), which acts by inhibiting mycolic acid biosynthesis, is very potent against the tuberculous mycobacteria. It is about 100-fold less effective against Mycobacterium avium. This difference has often been attributed to a decreased permeability of the cell wall. We measured the rate o...
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