Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Central carbon metabolism remodeling as a mechanism to develop drug tolerance and drug resistance in Mycobacterium tuberculosis

22 Aug 2022

Abstract excerpt

(Mtb), an etiological agent of tuberculosis (TB), render TB the world's deadliest infectious disease before the COVID-19 outbreak. Our outdated TB treatment method is designed to eradicate actively replicating populations of Mtb. Unfortunately, accumulating evidence suggests that a small population of Mtb can survive antimycobacterial pressure of antibiotics by entering a "persister" state (slowly replicating or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer therapeutics and mechanisms
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36072228
DOI: 10.3389/fcimb.2022.958240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Central carbon metabolism remodeling as a mechanism to develop drug tolerance and drug resistance in Mycobacterium tuberculosisPMID 36072228Read ↗

Tuberculosis metabolomics reveals adaptations of man and microbe in order to outcompete and surviveSemantic proximity Read ↗

Global adaptation to a lipid environment triggers the dormancy-related phenotype of Mycobacterium tuberculosis.Semantic proximity Read ↗

Mycobacterium tuberculosis MetabolismSemantic proximity Read ↗

Metabolic regulation of mycobacterial growth and antibiotic sensitivity.Semantic proximity Read ↗

Mycobacterium tuberculosis Proteome Response to Antituberculosis Compounds Reveals Metabolic “Escape” Pathways That Prolong Bacterial SurvivalSemantic proximity Read ↗

Mechanisms of Drug-Induced Tolerance in Mycobacterium tuberculosis.Semantic proximity Read ↗

Noise in a Metabolic Pathway Leads to Persister Formation in Mycobacterium tuberculosisSemantic proximity Read ↗

Drug-Tolerant Mycobacterium tuberculosis Adopt Different Survival Strategies in Alveolar Macrophages of Patients with Pulmonary TuberculosisSemantic proximity Read ↗

A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen.Semantic proximity Read ↗

Systems level mapping of metabolic complexity in Mycobacterium tuberculosis to identify high-value drug targets.Semantic proximity Read ↗

Metabolomics of Central Carbon Metabolism in <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Dissecting Host-Pathogen Interactions in TB Using Systems-Based Omic ApproachesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.