Article
Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance.
Antimicrobial agents and chemotherapy - 1 Sept 2010
Valderramos Stephanie Gaw, Scanfeld Daniel, Uhlemann Anne-Catrin, Fidock David A, Krishna Sanjeev
Abstract excerpt
Artemisinin-based combination therapies (ACTs) are highly effective for the treatment of Plasmodium falciparum malaria, yet their sustained efficacy is threatened by the potential spread of parasite resistance. Recent studies have provided evidence that artemisinins can inhibit the function of Pf...
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