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TGFβ1 rs1800469 and SMAD4 rs10502913 polymorphisms and genetic susceptibility to colorectal cancer in Bangladeshi population.

Molecular biology reports - 1 Feb 2023

Sultana Taposhi Nahid, Chaity Nusrat Islam, Hasan Md Mehedi, Shrabonee Ishrat Islam, Rivu Sanzana Fareen, Aziz Md Abdul, Sahaba Shaid All, Apu Mohd Nazmul Hasan, Nahid Noor Ahmed, Islam Mohammad Safiqul, Islam Md Saiful

Abstract excerpt

BACKGROUND: Among Bangladeshi males and females, colorectal cancer is the fourth and fifth most prevalent cancer, respectively. Several studies have shown that the transforming growth factor beta 1 (TGFβ1) gene and SMAD4 gene have a great impact on colorectal cancer. OBJECTIVE: The present study aimed to investigate whether TGFβ1 rs1800469 and SMAD4 rs10502913 genetic polymorphisms are associated with...

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PMID: 36469259
DOI: 10.1007/s11033-022-08146-x

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