Article
Predictors of parkin mutations in early-onset Parkinson disease: the consortium on risk for early-onset Parkinson disease study.
Archives of neurology - 1 Jun 2010
Marder Karen S, Tang Ming X, Mejia-Santana Helen, Rosado Llency, Louis Elan D, Comella Cynthia L, Colcher Amy, Siderowf Andrew D, Jennings Danna, Nance Martha A, Bressman Susan, Scott William K, Tanner Caroline M, Mickel Susan F, Andrews Howard F, Waters Cheryl, Fahn Stanley, Ross Barbara M, Cote Lucien J, Frucht Steven, Ford Blair, Alcalay Roy N, Rezak Michael, Novak Kevin, Friedman Joseph H, Pfeiffer Ronald F, Marsh Laura, Hiner Brad, Neils Gregory D, Verbitsky Miguel, Kisselev Sergey, Caccappolo Elise, Ottman Ruth, Clark Lorraine N
Abstract excerpt
BACKGROUND: Mutations in the parkin gene are the most common genetic cause of early-onset Parkinson disease (PD). Results from a multicenter study of patients with PD systematically sampled by age at onset have not been reported to date. OBJECTIVE: To determine risk factors associated with carryi...
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