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Article

Parkin mutations and early-onset parkinsonism in a Taiwanese cohort.

Archives of neurology - 1 Jan 2005

Wu Ruey-Meei, Bounds Rebecca, Lincoln Sarah, Hulihan Mary, Lin Chin-Hsien, Hwu Wuh-Liang, Chen Judy, Gwinn-Hardy Katrina, Farrer Matt

Abstract excerpt

BACKGROUND: Loss of function of the parkin gene (PRKN) is the predominant genetic cause of juvenile and early-onset parkinsonism in Japan, Europe, and the United States. OBJECTIVES: To evaluate the frequency of PRKN mutations in Taiwanese (ethnic Chinese) patients with early-onset parkinsonism and to explore genotype-phenotype correlations. DESIGN: Clinical assessment included medical, neurologic, and psychiatric...

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Source

Identifiers

PMID: 15642853
DOI: 10.1001/archneur.62.1.82

Genes

PRKN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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