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Article

Age of onset of mesial temporal lobe epilepsy with hippocampal sclerosis: the effect of apolipoprotein E and febrile seizures.

The International journal of neuroscience - 1 Sept 2017

Leal Bárbara, Chaves João, Carvalho Cláudia, Bettencourt Andreia, Freitas Joel, Lopes João, Ramalheira João, Costa Paulo P, Mendonça Denisa, Silva António M, Silva Berta M

Abstract excerpt

PURPOSE: Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is the most frequent pharmaco-resistant epilepsy. It has been associated with febrile seizures (FS) in childhood. Its aetiology remains unclear but genetic factors are involved. Apolipoprotein E (ApoE) is the main lipoprotein secreted in brain. It has a critical immunomodulatory function, influences neurotransmission and it is involved in...

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Identifiers

PMID: 27875923
DOI: 10.1080/00207454.2016.1264396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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