Article
Identifying regulatory relationships among genomic loci, biological pathways, and disease.
Artificial intelligence in medicine - 1 Jul 2010
Woo Jung Hoon, Cho Sung Bum, Lee Eunjee, Kim Ju Han
Abstract excerpt
OBJECTIVE: Elucidating genetic factors of complex diseases is one of the most important challenges in biomedical research. Recently, a genetical genomics approach of mapping genotype to transcripts has been used in complex disease analysis. This approach treats messenger ribonucleic acid (mRNA) expression as a quantitative trait and identifies putative regulatory loci for the expression of an individual gene....
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