Article
Gene co-expression analysis for functional classification and gene-disease predictions.
Briefings in bioinformatics - 20 Jul 2018
van Dam Sipko, Võsa Urmo, van der Graaf Adriaan, Franke Lude, de Magalhães João Pedro
Abstract excerpt
Gene co-expression networks can be used to associate genes of unknown function with biological processes, to prioritize candidate disease genes or to discern transcriptional regulatory programmes. With recent advances in transcriptomics and next-generation sequencing, co-expression networks constructed from RNA sequencing data also enable the inference of functions and disease associations for non-coding genes...
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