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Article

Localizing putative markers in genetic association studies by incorporating linkage disequilibrium into bayesian hierarchical models.

Human heredity - 1 Jan 2010

Fridley Brooke L, Jenkins Gregory D

Abstract excerpt

OBJECTIVE: Numerous methods have been proposed to model the association between multiple single nucleotide polymorphisms (SNPs) and a phenotype. Often these methods do not explicitly model the information regarding the linkage disequilibrium (LD) between SNPs. Furthermore, many methods shrink the SNP effects towards zero, rather than to an unknown latent gene-level effect. METHODS: We outline the use of bayesian...

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Identifiers

PMID: 20551675
DOI: 10.1159/000313852
PMCID: PMC2918651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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