Article
Gene trap mutation of murine outer dense fiber protein-2 gene can result in sperm tail abnormalities in mice with high percentage chimaerism.
BMC developmental biology - 15 Jun 2010
Tarnasky Heide, Cheng Min, Ou Young, Thundathil Jacob C, Oko Richard, van der Hoorn Frans A
Abstract excerpt
BACKGROUND: Outer dense fiber protein 2, Odf2, is a major component of the outer dense fibers, ODF, in the flagellum of spermatozoa. ODF are associated with microtubule doublets that form the axoneme. We recently demonstrated that tyrosine phosphorylation of Odf2 is important for sperm motility....
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