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Article

Haploinsufficiency for the murine orthologue of Chlamydomonas PF20 disrupts spermatogenesis

24 Aug 2004

Abstract excerpt

PF20 was first identified in Chlamydomonas rheinhardtii as an essential component of the axoneme central apparatus. We discovered that the mouse Pf20 gene encodes two major transcripts (2.5 and 1.4 kb), which are expressed in different patterns during spermatogenesis, yielding proteins of 71 and 35 kDa, respectively. Both proteins contain contiguous WD repeats in their C termini. The meiotically expressed 71-kDa...

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PMID: 15328412
DOI: 10.1073/pnas.0404280101

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