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Article

The small heat shock protein ODF1/HSPB10 is essential for tight linkage of sperm head to tail and male fertility in mice.

Molecular and cellular biology - 1 Jan 2012

Yang Kefei, Meinhardt Andreas, Zhang Bing, Grzmil Pawel, Adham Ibrahim M, Hoyer-Fender Sigrid

Abstract excerpt

Sperm motility and hence male fertility strictly depends on proper development of the sperm tail and its tight anchorage to the head. The main protein of sperm tail outer dense fibers, ODF1/HSPB10, belongs to the family of small heat shock proteins that function as molecular chaperones. However, the impact of ODF1 on sperm tail formation and motility and on male fecundity is unknown. We therefore generated mutant...

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Source

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Identifiers

PMID: 22037768
DOI: 10.1128/MCB.06158-11
PMCID: PMC3255718

Genes

ODF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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