Article
Alcohol binding to the odorant binding protein LUSH: multiple factors affecting binding affinities.
Biochemistry - 27 Jul 2010
Ader Lauren, Jones David N M, Lin Hai
Abstract excerpt
Density function theory (DFT) calculations have been carried out to investigate the binding of alcohols to the odorant binding protein LUSH from Drosophila melanogaster. LUSH is one of the few proteins known to bind to ethanol at physiologically relevant concentrations and where high-resolution structural information is available for the protein bound to alcohol at these concentrations. The structures of the...
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