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Article

Original encounter with antigen determines antigen-presenting cell imprinting of the quality of the immune response in mice.

PloS one - 7 Dec 2009

Abadie Valérie, Bonduelle Olivia, Duffy Darragh, Parizot Christophe, Verrier Bernard, Combadière Béhazine

Abstract excerpt

BACKGROUND: Obtaining a certain multi-functionality of cellular immunity for the control of infectious diseases is a burning question in immunology and in vaccine design. Early events, including antigen shuttling to secondary lymphoid organs and recruitment of innate immune cells for adaptive immune response, determine host responsiveness to antigens. However, the sequence of these events and their impact on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19997562
DOI: 10.1371/journal.pone.0008159
PMCID: PMC2785484

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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