[Construction of haplotype and haplotype block based on tag single nucleotide polymorphisms and their applications in association studies].

Abstract excerpt

Human genome has structures of haplotype and haplotype block which provide valuable information on human evolutionary history and may lead to the development of more efficient strategies to identify genetic variants that increase susceptibility to complex diseases. Haplotype block can be divided into discrete blocks of limited haplotype diversity. In each block, a small fraction of ptag SNPsq can be used to...

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