Article
Substantial correlation between HIV type 1 drug-associated resistance mutations in plasma and peripheral blood mononuclear cells in treatment-experienced patients.
AIDS research and human retroviruses - 20 Jul 2000
Devereux H L, Loveday C, Youle M, Sabin C A, Burke A, Johnson M
Abstract excerpt
The correlation of detectable HIV-1 drug resistance mutations in plasma and PBMCs in patients extensively treated with all antiretroviral drug classes has not been fully elucidated. The detection of mutations in PBMCs may reveal resistant HIV-1 associated with past therapies. In addition, these m...
Topics
- Anti-HIV Agents
- Codon
- DNA, Viral
- Drug Resistance, Microbial
- Drug Therapy, Combination
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Leukocytes, Mononuclear
- Molecular Sequence Data
- Mutation
- Reverse Transcriptase Inhibitors