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Article

Assembly of 5S ribosomal RNA is required at a specific step of the pre-rRNA processing pathway.

The Journal of cell biology - 28 Jun 1999

Dechampesme A M, Koroleva O, Leger-Silvestre I, Gas N, Camier S

Abstract excerpt

A collection of yeast strains surviving with mutant 5S RNA has been constructed. The mutant strains presented alterations of the nucleolar structure, with less granular component, and a delocalization of the 25S rRNA throughout the nucleoplasm. The 5S RNA mutations affected helix I and resulted in decreased amounts of stable 5S RNA and of the ribosomal 60S subunits. The shortage of 60S subunits was due to a...

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Identifiers

PMID: 10385518
DOI: 10.1083/jcb.145.7.1369
PMCID: PMC2133170

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Source receipt: pubmed, retrieved 7 Sept 2026.

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